Depending on your health, cost of your trip and your travel destination, you may want to consider travel insurance. Make sure you shop around to understand all your options before you make any decisions. Do this before buying or committing to any plane tickets, car rentals, hotels or other travel purchases.
My wife and I went to Italy last year so I did a bunch of checking around to see what the least expensive options were for the various aspects of the trip.
First check with your credit cards, you may be pleasantly surprised that you already have some form of travel insurance if the purchase for travel is done with that credit card so call your credit card company. I learned that my credit card offered travel insurance free of charge. There were restrictions on what they covered so read the fine print. Also see if your credit card company covers auto insurance for any rentals.